Acteur Rhys Ifans heeft een grote rol in The Amazing Spider-man. In de film verliest speelt hij namelijk Dr. Curt Connors. Het personage verliest zijn arm en raakt vervolgens geobsedeerd met het vermogen van sommige hagedissen om verloren ledematen weer opnieuw aan te groeien. Wat blijkt is dat Ifans niet alleen Connors speelde, maar in tegenstelling tot wat de bedoeling was, ook het personage Lizard.

"The majority of the time I'm me, I'm a human, not a Lizard. That's hard enough. I did have the CGI suit for certain scenes. The Lizard is 9 feet tall. There was one day that I went on set and they had a double, a big big guy, playing me, as the Lizard. I looked at it and I went "No." Following that Marc [Webb, the director] let me know all the physicality, all the physicality you'll see in the Lizard is my own.

I had a green suit on, and then this cardboard head, and these big claws. It was the most fucking insane… Each and every time you see the Lizard, the technology is so advanced now that when the Lizard's eyes move, they're my eyes. If I frown or show any emotion, they're my emotions. That's how spectacularly advanced technology is."

The Amazing Spider-Man draait vanaf 4 juli 2012 in de Nederlandse bioscopen.