Met Scream 4 lijkt Wes Craven wederom veel succes te behalen. De studio ziet het namelijk wel zitten dat er een volledig nieuwe Scream-trilogie komt. Dit was halverwege het vorige jaar, toen pas net bekend was dat Scream 4 er zou komen, al het gerucht, maar daarna is er nooit meer iets over gezegd.
Nu spreek Craven er dus wel over: "The studio wants to be very, very secretive about it," Craven admitted. "I think it's kind of known that Neve is returning to her hometown for a short visit, and all hell breaks loose. But there's also a whole cast of new characters -- there's some very, very interesting kids."
"It is or was a planned trilogy. I think the studio is realistic enough to say, let's see how it does," Craven said. But Kevin Williamson [the series creator and screenwriter] does have an idea for a planned trilogy out of it."
Vooralsnog is het echter wachten op Scream 4, die vanaf 28 april 2011 in de bioscopen draait.